Fibronodular hyperplasia FNH

It is the most common benign liver tumor after hemangiomas in the liver.

It is more common in women, but it has not been shown to be related to female hormones or the use of oral contraceptives.

Its prevalence in the community is between 0.03 and 3 percent.


It is mostly seen in images such as ultrasound, tomography or MRI taken for other reasons. For the most part, they do not complain. In rare cases, it can manifest itself with abdominal pain.

Usually their size does not exceed 5 centimeters.

Hepatocellular adenoma, hepatocellular carcinoma, fibrolamellar carcinoma can be counted in the differential diagnosis.

Unlike FNH lesions, hepatic adenomas do not contain kupffer cells and bile duct cells, so they are easily separated in contrast-enhanced MRI scans.

In contrast-enhanced MRI, FNH, which appears hypodense with respect to the liver before contrast is given, appears hyperintense in the arterial phase after contrast is given. Then, if the portal is excessive, it becomes isodense with the liver tissue. On later images, the central lesion appears hyperintense due to late contrast enhancement in the fibrous bands in the central scar area.

There is no need for treatment in FNH lesions that do not cause complaints. For this reason, it is not recommended for follow-up in lesions that do not cause complaints.

Abone olunuz

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