Ulcer is the circumstance that is caused by peeling of the cover-shaped epithelial tissue on the surface of the stomach due to excessive acid or irritant chemical and deepening the wound.
Aggressive factors in the formation of gastric ulcers:
- Helicobacter pylori
- Painkillers and aspirin
- Bile reflux
- Stress ulcers
- Zollinger Ellison syndrome
Preventative factors in preventing gastric ulcers include:
- release of bicarbonate of the stomach
- release of mucus in the stomach
- good mucosal blood build up
If we review the normal physiology of the stomach, acid is released from parietal cells in the stomach and pepsin is released from the chief cells and foods are digested. Meanwhile, the mucus released from epithelial cells is laid like a cover on the surface so as not to digest stomach’s own surface. This prevents bicarbonate acid and pepsin, which are secreted into the mucus layer and mucus layer, from giving touch and damage to the stomach surface.
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